Ewing Sarcoma Treatment

Ewing’s sarcoma is a malignant tumour that usually affects the bones. Among malignant bone tumors in children, it ranks second in frequency of occurrence after osteosarcoma. It most often occurs in long bones (such as femur, tibia, fibula, humerus), as well as in the pelvic bones, ribs, vertebrae, shoulder blades, etc. Flat bones such as the bones of the pelvis, ribs, or scapula are much more common with Ewing’s sarcoma than with osteosarcoma. From the primary bone focus, the tumor quickly spreads to the surrounding soft tissues, including muscles and tendons. Ewing’s sarcoma is rare children under 5 and adults over 30. Most often it occurs in adolescents 10-15 years old. Boys get sick more often than girls.

Symptoms of the disease

A characteristic symptom of Ewing’s bone sarcoma is a pain in the affected area of ​​the bone. Unlike pain caused by trauma, they do not subside when the limb is fixed, and over time they do not diminish, but intensify. Sometimes these pains are mistaken for a sign of inflammation, but antibiotics do not stop them.

In most patients with Ewing’s bone sarcoma and in almost all patients with extraosseous sarcoma, swelling gradually develops at the site of the tumor. The swelling can spread to the nearest joint, disrupting its function. The area of ​​swelling is usually painful to touch (palpation) and rapidly increases in size over time. With significant tumor damage to the bone, a pathological (that is, disease-induced) fracture of this bone may occur. As the tumor spreads in the body (metastasis), symptoms of a “general” nature appear weakness, fatigue, weight loss, and fever.

Treatment of pathology

Tel Aviv Medical Clinic, Israel’s leading clinic, employs qualified specialists who have been engaged in the diagnosis and treatment of pathology for more than 10 years. We use unique therapy methods and modern equipment. Our doctors annually undergo training in foreign clinics and know how to establish friendly contact with a child.

Ewing’s sarcoma is usually treated first with chemotherapy, followed by surgery and / or radiation therapy. Clinical trials are exploring new treatments: targeted therapy and immunotherapy. The main goals of disease therapy are:

• Reducing the size of the primary tumor and killing all circulating cancer cells with systemic chemotherapy
• Removing the primary tumor with surgery and / or radiation
• Treatment of remaining cancer with chemotherapy to reduce the risk of recurrence.